Publications

Peer-Reviewed Research Articles and Reviews 68. Reduces LPS-Mediated Inflammation and Induces Autophagy of Microglia. Affram, K. O., Janatpour, Z. C., Shanbhag, N., Villapol, S., & Symes, A. J. (2024). Telmisartan Neuroglia, 5(2), 182-201. https://doi.org/10.3390/neuroglia5020014 67. Gut microbiome dysbiosis and immune activation correlate with somatic and neuropsychiatric symptoms in COVID-19 patients: Microbiome dysbiosis linked to COVID-19 symptoms. Scalzo PL, Marshall A, Soriano S, Curry K, Dulay M, Hodics T, Quigley EM, Treangen TJ, Piskorz MM, Villapol S.medRxiv [Preprint]. 2024 Nov 19:2024.11.18.24317428. doi: 10.1101/2024.11.18.24317428.PMID: 39606341 Free PMC article. Preprint. 66. Nanotechnology-driven therapies for neurodegenerative diseases: a comprehensive review. López-Espinosa J, Park P, Holcomb M, Godin B, Villapol S.Ther Deliv. 2024;15(12):997-1024. doi: 10.1080/20415990.2024.2401307. Epub 2024 Sep 19.PMID: 39297726 Review. 65. Probiotic therapy modulates the brain-gut-liver microbiota axis in a mouse model of traumatic brain injury. Amaral WZ, Kokroko N, Treangen TJ, Villapol S, Gomez-Pinilla F.Biochim Biophys Acta Mol Basis Dis. 2024 Dec;1870(8):167483. doi: 10.1016/j.bbadis.2024.167483. Epub 2024 Aug 28.PMID: 39209236 Free PMC article. 64. Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice. Baudo G, Flinn H, Holcomb M, Tiwari A, Soriano S, Taraballi F, Godin B, Zinger A, Villapol S.Bioeng Transl Med. 2024 Feb 4;9(4):e10647. doi: 10.1002/btm2.10647. eCollection 2024 Jul.PMID: 39036088 Free PMC article. 63. Antibiotic treatment induces microbiome dysbiosis and reduction of neuroinflammation following traumatic brain injury in mice. Flinn H, Marshall A, Holcomb M, Cruz L, Soriano S, Treangen TJ, Villapol S.Res Sq [Preprint]. 2024 Jun 11:rs.3.rs-4475195. doi: 10.21203/rs.3.rs-4475195/v1.PMID: 38946944 Free PMC article. Preprint. 62. Antibiotic treatment induces microbiome dysbiosis and reduction of neuroinflammation following traumatic brain injury in mice. Flinn H, Marshall A, Holcomb M, Cruz L, Soriano S, Treangen TJ, Villapol S.Res Sq [Preprint]. 2024 Jun 11:rs.3.rs-4475195. doi: 10.21203/rs.3.rs-4475195/v1.PMID: 38946944
61. Probiotic treatment causes sex-specific neuroprotection after traumatic brain injury in mice. Holcomb M, Marshall A, Flinn H, Lozano M, Soriano S, Gomez-Pinilla F, Treangen TJ, Villapol S.Res Sq [Preprint]. 2024 Apr 2:rs.3.rs-4196801. doi: 10.21203/rs.3.rs-4196801/v1.PMID: 38645104 Free PMC article. Preprint.
60. Microbial Community Profiling Protocol with Full-length 16S rRNA Sequences and Emu. Curry KD, Soriano S, Nute MG, Villapol S, Dilthey A, Treangen TJ.Curr Protoc. 2024 Mar;4(3):e978. doi: 10.1002/cpz1.978.PMID: 38511467
59. iDISCO Tissue Clearing Whole-Brain and Light Sheet Microscopy for High-Throughput Imaging in a Mouse Model of Traumatic Brain Injury. Flinn H, Cruz-Pineda L, Montier L, Horner PJ, Villapol S.Methods Mol Biol. 2024;2761:589-597. doi: 10.1007/978-1-0716-3662-6_39.PMID: 38427263
58. Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice. Baudo G, Flinn H, Holcomb M, Tiwari A, Soriano S, Taraballi F, Godin B, Zinger A, Villapol S. bioRxiv. 2023 May 17:2023.05.16.541045. doi: 10.1101/2023.05.16.541045. Preprint. PMID: 37292856
57. The Renin Angiotensin System as a Therapeutic Target in Traumatic Brain Injury. Villapol S, Janatpour ZC, Affram KO, Symes AJ. Neurotherapeutics. 2023 Sep 27. doi: 10.1007/s13311-023-01435-8. Online ahead of print. PMID: 37759139 Review.
56. A multinational Delphi consensus to end the COVID-19 public health threat. Lazarus JV, Romero D, Kopka CJ, Karim SA, Abu-Raddad LJ, Almeida G, Baptista-Leite R, Barocas JA, Barreto ML, Bar-Yam Y, Bassat Q, Batista C, Bazilian M, Chiou ST, Del Rio C, Dore GJ, Gao GF, Gostin LO, Hellard M, Jimenez JL, Kang G, Lee N, Matičič M, McKee M, Nsanzimana S, Oliu-Barton M, Pradelski B, Pyzik O, Rabin K, Raina S, Rashid SF, Rathe M, Saenz R, Singh S, Trock-Hempler M, Villapol S, Yap P, Binagwaho A, Kamarulzaman A, El-Mohandes A; COVID-19 Consensus Statement Panel. Nature. 2022 Nov;611(7935):332-345. doi: 10.1038/s41586-022-05398-2. Epub 2022 Nov 3. PMID: 36329272
55. Emu: species-level microbial community profiling of full-length 16S rRNA Oxford Nanopore sequencing data. Curry KD, Wang Q, Nute MG, Tyshaieva A, Reeves E, Soriano S, Wu Q, Graeber E, Finzer P, Mendling W, Savidge T, Villapol S, Dilthey A, Treangen TJ.Nat Methods. 2022 Jul;19(7):845-853. doi: 10.1038/s41592-022-01520-4. Epub 2022 Jun 30.PMID: 35773532.
54. Long-COVID in children and adolescents: a systematic review and meta-analyses. Lopez-Leon S, Wegman-Ostrosky T, Ayuzo Del Valle NC, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S.Sci Rep. 2022 Jun 23;12(1):9950. doi: 10.1038/s41598-022-13495-5.PMID: 35739136.
53. Vaccinate fast but leave no one behind: a call to action for COVID-19 vaccination in Spain. Lazarus JV, Bassat Q, Crespo J, Fanjul G, Garcia-Basteiro AL, Hoyos ML, Mateos C, Gutierrez JM, Naniche D, Oliu-Barton M, Rabin KH, Vilasanjuan R, Villapol S, Martin-Moreno JM.Commun Med (Lond). 2021 Jul 7;1:12. doi: 10.1038/s43856-021-00014-2. eCollection 2021.PMID: 35602186
52. Fecal Microbiota Transplantation Derived from Alzheimer’s Disease Mice Worsens Brain Trauma Outcomes in Wild-Type Controls. Soriano S, Curry K, Wang Q, Chow E, Treangen TJ, Villapol S.Int J Mol Sci. 2022 Apr 19;23(9):4476. doi: 10.3390/ijms23094476.PMID: 35562867
51. Alterations to the gut microbiome after sport-related concussion in a collegiate football players cohort: A pilot study. Soriano S, Curry K, Sadrameli SS, Wang Q, Nute M, Reeves E, Kabir R, Wiese J, Criswell A, Schodrof S, Britz GW, Gadhia R, Podell K, Treangen T, Villapol S.Brain Behav Immun Health. 2022 Mar 1;21:100438. doi: 10.1016/j.bbih.2022.100438. eCollection 2022 May.PMID: 35284846
50. A contemporary review of therapeutic and regenerative management of intracerebral hemorrhage. Sadaf H, Desai VR, Misra V, Golanov E, Hegde ML, Villapol S, Karmonik C, Regnier-Golanov A, Sayenko D, Horner PJ, Krencik R, Weng YL, Vahidy FS, Britz GW.Ann Clin Transl Neurol. 2021 Nov;8(11):2211-2221. doi: 10.1002/acn3.51443. Epub 2021 Oct 14.PMID: 34647437 Free PMC article. Review.
49. Biomimetic Nanoparticles as a Theranostic Tool for Traumatic Brain Injury.Zinger A, Soriano S, Baudo G, De Rosa E, Taraballi F, Villapol S.Adv Funct Mater. 2021 Jul 23;31(30):2100722. doi: 10.1002/adfm.202100722. Epub 2021 Mar 26.PMID: 34413716 Free PMC article.
48. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S.Sci Rep. 2021 Aug 9;11(1):16144. doi: 10.1038/s41598-021-95565-8.PMID: 34373540.
47. Natural tannin extracts supplementation for COVID-19 patients (TanCOVID): a structured summary of a study protocol for a randomized controlled trial. Molino S, Pisarevsky A, Mingorance FL, Vega P, Stefanolo JP, Repetti J, Ludueña G, Pepa P, Olmos JI, Fermepin MR, Uehara T, Villapol S, Savidge T, Treangen T, Viciani E, Castagnetti A, Piskorz MM.Trials. 2021 Apr 28;22(1):310. doi: 10.1186/s13063-021-05281-x.PMID: 33910614 Free PMC article.
46. COVID-SCORE Spain: Public perceptions of key government COVID-19 control measures. White TM, Cash-Gibson L, Martin-Moreno JM, Matesanz R, Crespo J, Alfonso-Sanchez JL, Villapol S, El-Mohandes A, Lazarus JV.Eur J Public Health. 2021 Apr 19:ckab066. doi: 10.1093/eurpub/ckab066. Online ahead of print.PMID: 33872348 Free PMC article.
45. More Than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo P, Cuapio A, Villapol S.Res Sq. 2021 Mar 1:rs.3.rs-266574. doi: 10.21203/rs.3.rs-266574/v1. Preprint.PMID: 33688642 Free PMC article. Updated.
44. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S.medRxiv. 2021 Jan 30:2021.01.27.21250617. doi: 10.1101/2021.01.27.21250617. Preprint.PMID: 33532785 Free PMC article. Updated.
43. SARS-CoV-2 genomic diversity and the implications for qRT-PCR diagnostics and transmission. Sapoval N, Mahmoud M, Jochum MD, Liu Y, Elworth RAL, Wang Q, Albin D, Ogilvie HA, Lee MD, Villapol S, Hernandez KM, Maljkovic Berry I, Foox J, Beheshti A, Ternus K, Aagaard KM, Posada D, Mason CE, Sedlazeck FJ, Treangen TJ.Genome Res. 2021 Apr;31(4):635-644. doi: 10.1101/gr.268961.120. Epub 2021 Feb 18.PMID: 33602693 Free PMC article.
42. Gastrointestinal symptoms associated with COVID-19: impact on the gut microbiome. Villapol S.Transl Res. 2020 Dec;226:57-69. doi: 10.1016/j.trsl.2020.08.004. Epub 2020 Aug 20.PMID: 32827705 Free PMC article. Review.
41. Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission. Sapoval N, Mahmoud M, Jochum MD, Liu Y, Elworth RAL, Wang Q, Albin D, Ogilvie H, Lee MD, Villapol S, Hernandez KM, Berry IM, Foox J, Beheshti A, Ternus K, Aagaard KM, Posada D, Mason CE, Sedlazeck F, Treangen TJ.bioRxiv. 2020 Jul 2:2020.07.02.184481. doi: 10.1101/2020.07.02.184481. Preprint.PMID: 32637955 Free PMC article. Updated.
40. Serum Amyloid A is Expressed in the Brain After Traumatic Brain Injury in a Sex-Dependent Manner. Soriano S, Moffet B, Wicker E, Villapol S.Cell Mol Neurobiol. 2020 Oct;40(7):1199-1211. doi: 10.1007/s10571-020-00808-3. Epub 2020 Feb 14.PMID: 32060858

39. Early Sex Differences in the Immune-Inflammatory Responses to Neonatal Ischemic Stroke. Villapol S, Faivre V, Joshi P, Moretti R, Besson VC, Charriaut-Marlangue C.Int J Mol Sci. 2019 Aug 4;20(15):3809. doi: 10.3390/ijms20153809.PMID: 31382688 Free PMC article.
38. Serum Amyloid A Protein as a Potential Biomarker for Severity and Acute Outcome in Traumatic Brain Injury. Wicker E, Benton L, George K, Furlow W, Villapol S.Biomed Res Int. 2019 Apr 16;2019:5967816. doi: 10.1155/2019/5967816. eCollection 2019.PMID: 31119176 Free PMC article.
37. Traumatic Brain Injury in Mice Induces Acute Bacterial Dysbiosis Within the Fecal Microbiome. Treangen TJ, Wagner J, Burns MP, Villapol S.Front Immunol. 2018 Nov 27;9:2757. doi: 10.3389/fimmu.2018.02757. eCollection 2018.PMID: 30546361 Free PMC article.
36. Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury. Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP.Mol Neurodegener. 2018 Apr 4;13(1):17. doi: 10.1186/s13024-018-0249-5.PMID: 29618365 Free PMC article.
35. Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics. Bozzelli PL, Alaiyed S, Kim E, Villapol S, Conant K.Neural Plast. 2018 Feb 4;2018:5735789. doi: 10.1155/2018/5735789. eCollection 2018.PMID: 29531525 Free PMC article. Review.
34. Glial- and Neuronal-Specific Expression of CCL5 mRNA in the Rat Brain. Lanfranco MF, Mocchetti I, Burns MP, Villapol S.Front Neuroanat. 2018 Jan 12;11:137. doi: 10.3389/fnana.2017.00137. eCollection 2017.PMID: 29375328 Free PMC article.
33. *Combination of Fluorescent in situ* Hybridization (FISH) and Immunofluorescence Imaging for Detection of Cytokine Expression in Microglia/Macrophage Cells. Fe Lanfranco M, Loane DJ, Mocchetti I, Burns MP, Villapol S.**Bio Protoc. 2017 Nov 20;7(22):e2608. doi: 10.21769/BioProtoc.2608.PMID: 29238736 Free PMC article.
32. Roles of Peroxisome Proliferator-Activated Receptor Gamma on Brain and Peripheral Inflammation.Villapol S.Cell Mol Neurobiol. 2018 Jan;38(1):121-132. doi: 10.1007/s10571-017-0554-5. Epub 2017 Oct 3.PMID: 28975471 Free PMC article. Review.
31. Temporal Changes in Cortical and Hippocampal Expression of Genes Important for Brain Glucose Metabolism Following Controlled Cortical Impact Injury in Mice. Zhou J, Burns MP, Huynh L, Villapol S, Taub DD, Saavedra JM, Blackman MR.Front Endocrinol (Lausanne). 2017 Sep 11;8:231. doi: 10.3389/fendo.2017.00231. eCollection 2017.PMID: 28955302 Free PMC article.
30. A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury. Main BS, Sloley SS, Villapol S, Zapple DN, Burns MP.J Vis Exp. 2017 Jun 20;(124):55713. doi: 10.3791/55713.PMID: 28654066 Free PMC article.
29. Sexual dimorphism in the inflammatory response to traumatic brain injury. Villapol S, Loane DJ, Burns MP.Glia. 2017 Sep;65(9):1423-1438. doi: 10.1002/glia.23171. Epub 2017 Jun 13.PMID: 28608978 Free PMC article.
28. Reduced cortical excitatory synapse number in APOE4 mice is associated with increased calcineurin activity. Neustadtl AL, Winston CN, Parsadanian M, Main BS, Villapol S, Burns MP.Neuroreport. 2017 Jul 5;28(10):618-624. doi: 10.1097/WNR.0000000000000811. PMID: 28542068
27. NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury. Barrett JP, Henry RJ, Villapol S, Stoica BA, Kumar A, Burns MP, Faden AI, Loane DJ.J Neuroinflammation. 2017 Mar 24;14(1):65. doi: 10.1186/s12974-017-0843-4.PMID: 28340575.
26. Protease-induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease-activated receptor 1. Allen M, Ghosh S, Ahern GP, Villapol S, Maguire-Zeiss KA, Conant K.Sci Rep. 2016 Oct 20;6:35497. doi: 10.1038/srep35497.PMID: 27762280 Free PMC article.
25. Consequences of hepatic damage after traumatic brain injury: current outlook and potential therapeutic targets. Villapol S.Neural Regen Res. 2016 Feb;11(2):226-7. doi: 10.4103/1673-5374.177720.PMID: 27073366 Free PMC article.
24. Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. Winston CN, Noël A, Neustadtl A, Parsadanian M, Barton DJ, Chellappa D, Wilkins TE, Alikhani AD, Zapple DN, Villapol S, Planel E, Burns MP.Am J Pathol. 2016 Mar;186(3):552-67. doi: 10.1016/j.ajpath.2015.11.006. Epub 2016 Feb 5.PMID: 26857506 Free PMC article.
23. Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin. De Magalhaes Filho CD, Kappeler L, Dupont J, Solinc J, Villapol S, Denis C, Nosten-Bertrand M, Billard JM, Blaise A, Tronche F, Giros B, Charriaut-Marlangue C, Aïd S, Le Bouc Y, Holzenberger M.J Cereb Blood Flow Metab. 2017 Feb;37(2):396-412. doi: 10.1177/0271678X15626718. Epub 2016 Jul 20.PMID: 26762506 Free PMC article.
22. Hepatic expression of serum amyloid A1 is induced by traumatic brain injury and modulated by telmisartan. Villapol S, Kryndushkin D, Balarezo MG, Campbell AM, Saavedra JM, Shewmaker FP, Symes AJ.Am J Pathol. 2015 Oct;185(10):2641-52. doi: 10.1016/j.ajpath.2015.06.016.PMID: 26435412 Free PMC article.
21. Neurorestoration after traumatic brain injury through angiotensin II receptor blockage. Villapol S, Balarezo MG, Affram K, Saavedra JM, Symes AJ.Brain. 2015 Nov;138(Pt 11):3299-315. doi: 10.1093/brain/awv172. Epub 2015 Jun 26.PMID: 26115674 Free PMC article.
20. Polypathology and dementia after brain trauma: Does brain injury trigger distinct neurodegenerative diseases, or should they be classified together as traumatic encephalopathy? Washington PM, Villapol S, Burns MP.Exp Neurol. 2016 Jan;275 Pt 3(0 3):381-388. doi: 10.1016/j.expneurol.2015.06.015. Epub 2015 Jun 16.PMID: 26091850 Free PMC article. Review.
19. Neuroprotective effects of angiotensin receptor blockers. Villapol S, Saavedra JM.Am J Hypertens. 2015 Mar;28(3):289-99. doi: 10.1093/ajh/hpu197. Epub 2014 Oct 31.PMID: 25362113 Review.
18. Temporal dynamics of cerebral blood flow, cortical damage, apoptosis, astrocyte-vasculature interaction and astrogliosis in the pericontusional region after traumatic brain injury. Villapol S, Byrnes KR, Symes AJ.Front Neurol. 2014 Jun 4;5:82. doi: 10.3389/fneur.2014.00082. eCollection 2014.PMID: 24926283 Free PMC article.
17. Temporal patterns of cortical proliferation of glial cell populations after traumatic brain injury in mice. Susarla BT, Villapol S, Yi JH, Geller HM, Symes AJ.ASN Neuro. 2014 May 8;6(3):159-70. doi: 10.1042/AN20130034.PMID: 24670035 Free PMC article.
16. Smad3 deficiency increases cortical and hippocampal neuronal loss following traumatic brain injury. Villapol S, Wang Y, Adams M, Symes AJ.Exp Neurol. 2013 Dec;250:353-65. doi: 10.1016/j.expneurol.2013.10.008. Epub 2013 Oct 9.PMID: 24120438
15. Commercially available angiotensin II At₂ receptor antibodies are nonspecific. Hafko R, Villapol S, Nostramo R, Symes A, Sabban EL, Inagami T, Saavedra JM.PLoS One. 2013 Jul 1;8(7):e69234. doi: 10.1371/journal.pone.0069234. Print 2013.PMID: 23840911 Free PMC article.
14. TGF-β superfamily gene expression and induction of the Runx1 transcription factor in adult neurogenic regions after brain injury. Logan TT, Villapol S, Symes AJ.PLoS One. 2013;8(3):e59250. doi: 10.1371/journal.pone.0059250. Epub 2013 Mar 21.PMID: 23555640 Free PMC article.
13. Inhaled nitric oxide reduces brain damage by collateral recruitment in a neonatal stroke model. Charriaut-Marlangue C, Bonnin P, Gharib A, Leger PL, Villapol S, Pocard M, Gressens P, Renolleau S, Baud O.Stroke. 2012 Nov;43(11):3078-84. doi: 10.1161/STROKEAHA.112.664243. Epub 2012 Sep 4.PMID: 22949477
12. Candesartan, an angiotensin II AT₁-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice. Villapol S, Yaszemski AK, Logan TT, Sánchez-Lemus E, Saavedra JM, Symes AJ.Neuropsychopharmacology. 2012 Dec;37(13):2817-29. doi: 10.1038/npp.2012.152. Epub 2012 Aug 15.PMID: 22892395 Free PMC article.
11. Dual action of NO synthases on blood flow and infarct volume consecutive to neonatal focal cerebral ischemia. Bonnin P, Leger PL, Villapol S, Deroide N, Gressens P, Pocard M, Renolleau S, Baud O, Charriaut-Marlangue C.Exp Neurol. 2012 Jul;236(1):50-7. doi: 10.1016/j.expneurol.2012.04.001. Epub 2012 Apr 12.PMID: 22531298
10. Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke. Villapol S, Fau S, Renolleau S, Biran V, Charriaut-Marlangue C, Baud O.Pediatr Res. 2011 Jan;69(1):51-5. doi: 10.1203/PDR.0b013e3181fcb40b.PMID: 20856166
9. Unilateral blood flow decrease induces bilateral and symmetric responses in the immature brain. Villapol S, Bonnin P, Fau S, Baud O, Renolleau S, Charriaut-Marlangue C.Am J Pathol. 2009 Nov;175(5):2111-20. doi: 10.2353/ajpath.2009.090257. Epub 2009 Oct 8.PMID: 19815715 Free PMC article.
8. Astrocytic demise in the developing rat and human brain after hypoxic-ischemic damage. Gelot A, Villapol S, Billette de Villemeur T, Renolleau S, Charriaut-Marlangue C.Dev Neurosci. 2009;31(5):459-70. doi: 10.1159/000232564. Epub 2009 Aug 11.PMID: 19672074
7. Astrocyte responses after neonatal ischemia: the yin and the yang. Villapol S, Gelot A, Renolleau S, Charriaut-Marlangue C.Neuroscientist. 2008 Aug;14(4):339-44. doi: 10.1177/1073858408316003. Epub 2008 Jul 8.PMID: 18612085 Review.
6. Substantial migration of SVZ cells to the cortex results in the generation of new neurons in the excitotoxically damaged immature rat brain. Faiz M, Acarin L, Villapol S, Schulz S, Castellano B, Gonzalez B.Mol Cell Neurosci. 2008 Jun;38(2):170-82. doi: 10.1016/j.mcn.2008.02.002. Epub 2008 Mar 4.PMID: 18434192
5. Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain. Villapol S, Acarin L, Faiz M, Castellano B, Gonzalez B.Neuroscience. 2008 Apr 22;153(1):108-19. doi: 10.1016/j.neuroscience.2008.01.054. Epub 2008 Feb 14.PMID: 1835862
4. Distinct spatial and temporal activation of caspase pathways in neurons and glial cells after excitotoxic damage to the immature rat brain. Villapol S, Acarin L, Faiz M, Castellano B, Gonzalez B.J Neurosci Res. 2007 Dec;85(16):3545-56. doi: 10.1002/jnr.21450.PMID: 17668855
3. Bilateral changes after neonatal ischemia in the P7 rat brain. Spiegler M, Villapol S, Biran V, Goyenvalle C, Mariani J, Renolleau S, Charriaut-Marlangue C.J Neuropathol Exp Neurol. 2007 Jun;66(6):481-90. doi: 10.1097/01.jnen.0000263875.22306.3c.PMID: 17549008
2. Caspase-3 activation in astrocytes following postnatal excitotoxic damage correlates with cytoskeletal remodeling but not with cell death or proliferation. Acarin L, Villapol S, Faiz M, Rohn TT, Castellano B, González B.Glia. 2007 Jul;55(9):954-65. doi: 10.1002/glia.20518.PMID: 17487878
1. Antioxidant Cu/Zn SOD: expression in postnatal brain progenitor cells. Faiz M, Acarin L, Peluffo H, Villapol S, Castellano B, González B.Neurosci Lett. 2006 Jun 19;401(1-2):71-6. doi: 10.1016/j.neulet.2006.03.010. Epub 2006 Mar 29.PMID: 16567040

Book Chapters

1. Book: Trends in Cell Signaling Pathways in Neuronal fate decision. Role of TGF-β Signaling in Neurogenic Regions After Brain Injury. Sonia Villapol, Trevor T. Logan, Aviva J. Symes. ISBN 978-953-51-1059-0, Hard cover, 358 pages, Publisher: InTech, Published: March 27, 2013

2. Book: Amyloidosis. Neuropathology of traumatic brain injury and its role in the development of Alzheimer’s Disease. Sonia Villapol. IntechOpen, 2018. DOI: 10.5772/intechopen.81945.

3. Book: Concussion and Traumatic Encephalopathy. Polypathology and Dementia After Brain Trauma: Does Brain Injury Trigger Distinct Neurodegenerative Diseases, or Should They be Classified Together as Traumatic Encephalopathy Washington PM, Villapol S, Burns MP. Edited by Dr. Jeff Victoroff and Dr. Erin D. Bigler. Chapter 13, Pages 573-582, 2018. Cambridge University Press. ISBN: 9781139696432.

4. Book: Fisiopatología de la COVID-19 en diferentes órganos y sistemas. Sonia Villapol. 6.- ALTERACIONES GASTROINTESTINALES. 6.1.- Fisiopatología de las alteraciones gastrointestinales durante la infección por SARS-Cov2. 6.2.- Fisiopatología de las alteraciones hepáticas durante la infección por SARS-Cov2. Elsevier, fall 2021.

5. Book: Neuroprotection: Methods and Protocols of the series METHODS IN MOLECULAR BIOLOGY. “iDISCO tissue clearing whole-brain and light sheet microscopy for high-throughput imaging in a mouse model of traumatic brain injury”. Hannah Flinn, Leonardo Cruz-Pineda, Laura Montier, Philip J. Horner and Sonia Villapol. Springer Nature. 2023, in press.

6. Book: Understanding the Behavioral and Medical Impact of Long COVID: An Empirical Guide to Assessment and Treatment of Post-Acute Sequelae of SARS CoV-2 Infection. “Chapter 6. Gastrointestinal Disorders”. Sonia Villapol. Jason, L.A., & Lapp, C. (Eds.)(2022). New York, NY: Routledge.

7. Book: The role of the microbiota–gut–brain axis on the neurobiology of infectious diseases

GZ Réus, S Villapol, T Barichello – Neurobiology of Infectious Diseases, 2025

Publications

Peer-Reviewed Research Articles and Reviews

Book Chapters

1. Book: Trends in Cell Signaling Pathways in Neuronal fate decision. Role of TGF-β Signaling in Neurogenic Regions After Brain Injury. Sonia Villapol, Trevor T. Logan, Aviva J. Symes. ISBN 978-953-51-1059-0, Hard cover, 358 pages, Publisher: InTech, Published: March 27, 2013

2. Book: Amyloidosis. Neuropathology of traumatic brain injury and its role in the development of Alzheimer’s Disease. Sonia Villapol. IntechOpen, 2018. DOI: 10.5772/intechopen.81945.