Welcome to the VILLAPOL LAB!
Our lab pursues novel neurorestorative treatments for brain recovery through the lens of the periphery.
The Villapol Lab’s mission at Houston Methodist Research Institute is to look for novel neurorestorative treatments for brain recovery through the lens of the periphery.
Our lab studies the inflammatory and neurodegenerative mechanisms triggered after brain trauma or stroke in a sex-dependent manner. The laboratory is also investigating the contribution of peripheral signals and the gut microbiome to brain pathology.
Currently, we are using our resources and expertise to focus on understanding SARS-CoV-2 and COVID-19, to understand the role of the gut and oral microbiome in COVID-19 infection and prognosis.
Associate Editor, Springer Journal ‘Cellular and Molecular Neurobiology’
Sirena Soriano, PhD
Shashi Krishnamurthy, MS
Jane Fitzgerald, BS
Saeed Sadrameli, M.D.
November 27, 2018
Traumatic Brain Injury in Mice Induces Acute Bacterial Dysbiosis within the Fecal Microbiome
Frontiers in Immunology
The secondary injury cascade that is activated following traumatic brain injury (TBI) induces responses from multiple physiological systems, including the immune system. These responses are not limited to the area of brain injury; they can also …